LCMRC researchers have discovered that solutions in water of pieces of DNA only
a few nanometers long (nanoDNA) can form liquid crystal phases if the DNA is
complementary, that is if it can form double helixed pairs. These duplex pairs
then stack up end-to-end to form rod-shaped aggregates that make the liquid
crystal phases. In a mixture with some DNA that is not complementary the duplex-forming DNA phase separates, condensing into liquid crystal droplets. If
chemistry is present that couples the short DNA into longer chains then the
condensation strongly favors the lengthening of the already complementary DNA in
the liquid crystal droplets. This appears to be a mechanism whereby early forms
of nucleic acids could emerge from small chemical components in the prebiotic
earth.
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Liquid Crystals of nanoDNA |
